치아우식 발생에 대한 구강미생물과 당류의 영향에 관한 연구
STUDY ON THE EFFECT OF ORAL MICROORGANISMS AND SUGARS ON DENTAL CARIES
김종배, 백대일, 문혁수, 윤정원,
소속 상세정보
김종배 ( Kim Johng-Bai ) - 서울대학교 치과대학 예방치학교실
백대일 ( Paik Dai-Il ) - 서울대학교 치과대학 예방치학교실
문혁수 ( Moon Hyuck-Soo ) - 서울대학교 치과대학 예방치학교실
윤정원 ( Yoon Jeong-Weon ) - 수원대학교 공과대학 유전공학과
KMID : 0355419910150020209
Abstract
Dental caries is developed by acids produced by oral microorganisms, especially streptococcus mutans. In order to investigate the mechanism of decalcification, the authors had analyzed the effect of oral microorganism and sugar on dental caries.
The effects of radio-isotoped sucrose ((U-14C)sucrose) and metabolite of streptococcus mutans 10449C on decalcification of hydroxylapatite by using liquid scintillation counter was experimented. And also, the decalcified calcium ion concentration produced by oral microorganism was measured by using atomic absorption spectroscopy. The obtained results were as follows:
1. Oral streptococcus mutans seemed to develop decalcification by producing lactic acid from sucrose.
2. The decalcified calcium ion concentration from hydroxylapatite by streptococcus mutans was increased by concentration of sucrose and time.
3. It see that atomic absorption spectroscopy could be used accurately for studying the decalcification mechanism.
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